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When Is It Time to Adjust Your Mental Health Medication?

Jan 02, 2026
When Is It Time to Adjust Your Mental Health Medication?
Not sure if your mental health medication is still working for you? This quick read breaks down the subtle clues that you need an adjustment, what to do next, and how thoughtful changes can support real progress.

Finding the right mental health medication and the right dose is often a journey. Your physical health, brain chemistry, and daily life can change over time, and a medication that once supported you well might not continue to meet your needs in the same way.

At Ketamine Health & Wellness Clinics of Ohio, we often see patients who feel “stuck” in their current treatment plan but aren’t sure if it’s time for a change. Our team is here to help you recognize the signs that might mean you need some adjustments to your medication.

The goal is for you to feel balanced again. Here are six signs that might indicate you need a change to your mental health medication.

1. Your symptoms are returning or getting worse

If you’re having feelings of anxiety or depression, or if you notice mood swings returning, your medication might not be providing the same level of support it once did. Sometimes your body adapts to a medication, making it less helpful over time. 

This doesn’t mean you’ve done anything wrong; it simply may be time to reevaluate.

2. You’re experiencing new or worsening side effects

Medication side effects don’t always appear right away — they can develop gradually or become more noticeable as your dose changes or as your lifestyle shifts. If you’re experiencing fatigue, changes in weight, trouble sleeping, or a sense of emotional numbness, adjusting your medication may help you feel better while continuing to support your mental health.

3. You’re feeling overly sedated or emotionally flat

Are you having a difficulty with brain fog or feeling disconnected? This may be a sign that your medication dose is too high or that the type of medication isn’t the best fit for you. Your treatment should help you function, not limit your energy or joy.

4. You’re going through a major life change

Your mental health needs can change when you experience stressful or major life events, like starting a new job, experiencing trauma or loss, going through postpartum changes, or managing ongoing medical conditions. Medication that once managed your baseline symptoms may no longer be enough during these transitions.

5. You’ve hit a plateau in your healing

Sometimes progress stalls. You may feel as though you’re stable but not truly improving. If your medication keeps you from hitting emotional lows but doesn’t help you reach a better quality of life, an adjustment might open new possibilities.

6. You’re interested in exploring advanced options

If you haven’t found relief with traditional antidepressants or mood stabilizers, ketamine therapy can be a powerful next step. We offer ketamine intravenous treatment, which works differently from most standard medications. It targets your glutamate pathways and helps your brain rewire more quickly. 

If you haven’t responded well to typical treatments, you may find renewed hope with this option. Or, you may want to consider Spravato®, which is an intranasal treatment that’s a derivative of ketamine.  

Schedule a consultation

Adjusting medication isn’t a setback; it’s part of personalized, responsive mental healthcare. 

Led by an experienced psychiatrist, the Ketamine Health & Wellness Clinics of Ohio team offers medication management. We’re here to help you evaluate what’s working, what isn’t, and whether alternative treatments like ketamine therapy or Spravato could move you toward lasting relief. 

If something feels off, trust your instincts and make an appointment at our clinic in Dublin, Ohio. Reach out to our friendly office today by calling 380-214-1636, or click here to book an appointment online.