Advanced Psychiatric Care for Treatment-Resistant Depression

Ketamine Health & Wellness Clinics of Ohio provides physician-led care, SPRAVATO® treatment, IV ketamine therapy, and comprehensive psychiatric services in Dublin, Ohio.

We are committed to delivering innovative, evidence informed treatments and advancing that evidence through peer reviewed research.

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Peer-Reviewed Research From Our Clinic

Real-world evidence from the patients we treat

Results from our peer-reviewed study of adults with treatment-resistant depression.

SPRAVATO® (esketamine)
patients

83.8%

achieved clinically meaningful improvement in depression symptoms during induction treatment

IV ketamine
patients

73.1%

achieved clinically meaningful improvement in depression symptoms during induction treatment

Our study was published in
Frontiers in Psychiatry

July 9, 2026

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Clinically meaningful improvement was defined as a ≥5-point reduction in PHQ-9 score.
Results reflect a retrospective observational study of 63 patients treated at our clinic and do not predict individual outcomes.

Conditions We Treat

Treatment-Resistant
Depression

When traditional treatments aren't enough.

Anxiety Disorders

Including generalized anxiety, social anxiety, and panic disorder.

PTSD & Trauma
Related Disorders

Evidence-informed care for lasting relief.

Other Mood & Stress-
Related Conditions

Personalized care for your unique needs.

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Our Published Research

Real-world outcomes of intranasal esketamine and intravenous ketamine induction therapy for treatment-resistant depression in a community clinic

This retrospective cohort study evaluated outcomes among 63 adults with treatment-resistant depression who received intranasal esketamine or intravenous ketamine during induction treatment at our clinic.

Both treatment groups experienced substantial reductions in depression symptoms.
No serious adverse events were reported.
Findings support the real-world effectiveness and tolerability of these therapies.